author's abstract of his paper issced 

 by the bibliographic service, september 29 



THE EARLY HISTOGENESIS OF THE BLOOD IN BUFO 

 HALOPHILUS BAIRD AND GIRARD 



RALPH DOUGALL LILLIE 



Division of Anatomy of Stanford University Medical School 



SEVEN FIGURES 



CONTENTS 



Introduction and literature 209 



Material and methods 211 



The ventral cell mass 212 



The primitive blood-cells 214 



The stage of differentiation of the primitive blood-cells into primitive 



erythroblasts and large lymphocytes. The loss of the yolk 218 



The further differentiation of the primitive erythrocyte stem 221 



The hematopoietic tissue of the mesonephros 222 



Summary and conclusions 228 



Bibliography 230 



INTRODUCTION AND LITERATURE 



The histogenesis of the blood of Amphibia has occupied the 

 attention of but few writers. Among these the earlier ones and 

 Maximow ('10) in Rana hold that the primitive blood-cells give 

 rise only to red corpuscles, while in other vertebrates, such as 

 Lepidosiren (Bryce, '04), birds and Tropidonotus (Danchakoff, 

 '08 a, 16 a), Chelonia (Jordan and Flippin, '13), mammals (Max- 

 imow, '09 a, and Jordan, '10), and in certain Amphibia them- 

 selves, (Bufo, Mietens, '10), the same cells give rise to two lines 

 of descent, viz., an erythrocyte and a leucocyte stem. Further, 

 it has been shown that this erythrocyte stem is a transitory one, 

 giving place later to a definitive one which is a branch of the 

 leucocyte line. 



This difference between the Amphibia and other vertebrates 

 and especially between the two Amphibian forms, suggested the 



209 



