356 S. SAGUCHI 



way along or through the chromatin network, which is in accord 

 with what has been said concerning the position of the two. 



That the nucleolus is concerned in the production of the nu- 

 cleolar corpuscles or similar bodies has been noticed by Mont- 

 gomery ('99). This author, in a description of the subcuticular 

 gland cells of piscicola, pictures the nucleolus, after having en- 

 larged to a certain extent, as constricting off pieces of all shapes 

 and sizes, which are distributed through the nucleus; and that 

 this is not a picture of fusion of nucleolar corpuscles with the 

 nucleolus is apparent from the fact that they are all cast off into 

 the cytoplasm. On the other hand, the fuchsinophile granules 

 which were seen, by Galeotti ('95), in the nuclei of the Spelerpes' 

 pancreas and pyrenoid corpuscles which, after Meirowsky ('08), 

 appear in the nuclei in the formation of pigment, are, in all 

 probability, structures which have been constricted off of the 

 nucleolus or, at least, have the same origin as this. 



3. THE CELL-BODY 



A. Structure of the cytoplasm 



Observations. In studying the structure of the cell in general, 

 especially of the glandular cell, it seems to me to be most essential 

 to discriminate between two groups of the cytoplasmic contents; 

 to one group belongs the cytoplasm proper or protoplasm that 

 forms the ground-mass of the cell-body, and to the other, that 

 group formed by the vital activities of the former, or, derived 

 either from the nucleus or from the outside ; and, as instances of 

 the second group, mitochondrial granules or filaments, zymogen 

 granules, lipoid granules, etc., may be enumerated. In the fol- 

 lowing I will first take up the cytoplasm proper, while the other 

 constituents of the cell-body will be treated of separately. 



The existence of a large number of zymogen granules and mito- 

 chondrial apparatus often renders impossible satisfactory de- 

 tailed observation upon the cytoplasm proper. Under these cir- 

 cumstances, it will be advisable to examine a cell containing 

 only a few zymogen granules or such portions in which they are 

 generally wanting, i.e., the basal portion of the cell. Alveolar 



