406 S. SAGUCHI 



nificance of these corpuscles remains as yet undecided, in spite 

 of the fact that they have attracted much attention of those 

 investigators who were engaged in the study of the pancreas, is 

 due essentially to the fact that their genesis was not fully followed 

 out. In fact, there are some who regard the mebenkerne,' which 

 are spherical in shape and marked off sharply from the surround- 

 ing cytoplasm in which they are embedded, as products of the 

 chromatolysis (Melissinos and Nicolaides, Macallum, and Gar- 

 nier). Nevertheless, these investigators have failed to throw 

 light upon the process of their formation. The fact that these 

 corpuscles are found beside the nucleus within the normal cell 

 tends to contradict the view that they are products of the chro- 

 matolysis. This is perhaps the reason why Platner has taken 

 them to be produced by the partial degeneration of the nucleus, 

 and has named the process 'partial chromatolysis.' 



Kanazawa, Japan, June 15, 1918. 



