MITOCHONDRIA IN VERTEBRATE NERVE CELLS 21 



fuse appearance (chromatolysis). In other words, with the dis- 

 charge of function the concentration of the diffuse Nissl substance 

 is lessened and its coagulabihty decreased so that the aggregates 

 become smaller and smaller until finally no coagula result. The 

 amount of chromatolysis would be inversely proportional to 

 the concentration of the Nissl substance and its degree of 

 coagulability. 



RESULTS 



1. Mitochondria occur in the spinal ganglion cells of man, 

 monkey, guinea-pig, white rat, pigeon, snake, turtle, frog and 

 necturus, in which they are characterized by the constancy of 

 their morphology, distribution, relative amount and microchemi- 

 cal properties. 



2. There is a reciprocal relation between the amount of mito- 

 chondria and lipoid granules in the spinal ganglion cells of these 

 vertebrates. 



3. The coagulability of the Nissl substance, on fixation, in- 

 creases progressively in the gradation which exists between the 

 small and the large spinal ganglion cells of man, monkey, guinea- 

 pig and white rat. 



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