AUTHOR’S ABSTRACT OF THIS PAPER ISSUED BY 
THE BIBLIOGRAPHIC SERVICE, DECEMBER 23 
THE ORIGIN OF THE PHAGOCYTIC MONONUCLEAR 
CELLS OF THE PERIPHERAL BLOOD! 
FRANK A. McJUNKIN 
Department of Pathology, Marquette University School of Medicine, Milwaukee, 
Wisconsin 
ELEVEN FIGURES (THREE PLATES) 
CONTENTS 
dig MINIS TIGGER SU Ran enna ne 27 
a. Phagocytosis as a specialized function of certain cells............. 27 
b. The nature of carbon ingested under experimental conditions by 
FINA COC MU OST SPI ce ete aes taint SA cue ee che a RUE a oy uss o's. Sle 31 
ce. Conditions under which Rititoc fore of carbon takes place in vivo 34 
B. Experiments that show the origin of the phagocytic mononuclear cells of 
the blood from the endothelium of blood-vessels................. 36 
a. Limitation of ingested carbon to the phagocytic mononuclear 
leucocytes of the blood and the endothelial cells of small b!ood- 
WOES! IS Bis 6 A ci ED he ee bil de Ry ithe ti a ot fe ea ie oe ge 36 
b. Mitosis of carbon-containing endothelial cells in the walls of 
blood-vessels that are not lengthening.................. Ste 40 
ce. The phagocytic activity of immature myeloblastic cells.......... 41 
d. The possible origin of a certain number of the phagocytic mono- 
nuclear cells of the blood from the endothelial lining of lymph- 
OSES Soin ory htt Oa 0 co GO Dace Oe OTL CID ORE CILIA ET en a eee 42 
Ch NORGE ONE: AES Ea LE ne ee ee a 45 
A. INTRODUCTION 
a. Phagocytosis as a specialized function of certain cells 
In an earlier report by the writer (’18) about five per cent of 
phagocytic mononuclear cells are shown to be present in normal 
human blood. The purpose of the present paper is to trace 
the origin of the phagocytic mononuclear cells found in the 
blood from fixed tissue cells. Since the technic of the experi- 
ments employed for this purpose as well as that of the earlier 
1 A second report of Studies on the Mononuclear Cells of the Blood. 
27 
