144 DELLA DRIPS 
ovary has a lacy appearance. There are a few good-sized, apparently 
normal follicles and on the periphery are numbers of primordial ova. 
Experiment 445-15 (spermophile 249). Captured in the spring of 
1915. Weight, 110 grams. Operated on October 4, 1915. Complete 
removal of the uterus. 
Sacrificed April 22, 1916. 
Gross observations. The blood supply to the ovaries is intact. 
The ovaries are very small; the left so small as to leave doubt as to its 
identity. The right ovary appears to contain several tiny cysts. 
Microscopic observations of the ovaries. Fixative, formalin zenker. 
Stain, hematoxylin and eosin. Tissue removed for left ovary proves 
to be a bit of granulation tissue. The right ovary appears to be nor- 
mal. The several cysts noted grossly are large mature follicles which 
normally occur on the surfaces of the ovaries at this time of the year. 
No effects from the removal of the uterus are noted. 
Discussionand summary of results. There seemsto be no marked 
effect on the ovaries from the removal of the uterus They seem 
able to repeat their life cycle as far as the follicles are concerned. 
It was thought that the great number of hyalinized follicles noted 
in the ovaries of spermophile 248 was a sign of degeneration due 
to removal of the uterus. However, on studying the ovaries of 
normal spermophiles killed about the same time for controls, 
there were found in the ovaries of two a great number of these 
hyalinized follicles (fig. 11). Evidently the hyalin degeneration 
occurs normally at this time of the year. It is, no doubt, part 
of the attempt to produce a few large mature follicles at the 
expense 0 many smaller ones. 
Series 2. Effects of removal of the uterus on ovariés in pregnant 
animals 
Experiment 270-16 (spermophile 305). Captured May 1, 1916. 
Weight, 98 grams. Operated on May 4, 1916. The uterus was 
‘removed to the cervix. 
Gross observations. There are no signs of pregnancy in the uterus, 
but the right ovary contains what appears to be a hemorrhagic cyst. 
Died May 9, 1916. 
Gross observations. There was no apparent cause for death. 
Microscopic observations of one ovary. Fixative, formalin zenker. - 
Stain, hematoxylin and eosin. The ovary contains several corpora 
lutea of an early stage. One is markedly hemorrhagic. There is some 
degeneration apparent in the luteal bodies. Some cells are undergoing - 
chromatolysis. There is an increased amount of connective tissue. 
The rest of the ovary appears to be in a very normal condition. 
