156. - DELLA DRIPS 
Discussion and summary of results. Three spermophiles were 
operated on in this series. The results were positive. The 
removal of one ovary during the second half of pregnancy does 
not affect in any way the normal development of the fetuses. 
They go on to term. There is no effect produced on the re- 
maining ovary and the development of rts corpora lutea. 
rv 
Series 7. Effects on the remaining ovary of the removal of one 
ovary and the uterus in pregnant animals 
Experiment 273-16 (spermophile 308). Captured May 1, 1916. 
Operated on May 4, 1916. The right ovary and the uterus were 
removed. 
Gross observations. Three are four placental swellings in the right 
horn of the uterus and three in the left about 4.5 mm. in length. Both 
ovaries show hemorrhagic areas which look like tiny hemorrhagic 
cysts. They are more noticeable in the right ovary. 
Died May 11, 1916. 
Gross observations. Absolutely no cause for death is apparent in 
the abdomen. The blood-vessels to the remaining ovary are very 
much congested. 
Microscopic observations of the ovaries. Both ovaries: fixative, 
formalin zenker; stains, hematoxylin and eosin, acid fuchsin and 
methyl green, and Weigert’s copper-chrome-hematoxylin. The right 
ovary contains five corpora lutea of a very early stage, measuring 0.7 
mm.x 0.9mm. The left ovary contains four corpora lutea, measur- 
ing 0.8mm.x0.5mm. This organ shows no pathology except in the 
corpora lutea. These bodies show many degenerative changes. The 
cells have lost their red granules and their nuclei are undergoing chro- 
matolysis. The connective tissue has increased greatly. 
Experiment 290-16 (spermophile. 325). Captured May 4, 1916. 
Weight, 111 grams. Operated on May 6, 1916. The right ovary and 
uterus were removed. 
Gross observations. The animal is pregnant, the fetuses being just 
recognizable. 
Sacrificed June 8, 1916. 
Microscopic observations of the ovaries. Fixative, formalin zenker. 
Stain, acid fuchsin and methyl green. The right ovary contains five 
corpora lutea of a very early stage, about 0.5 mm. x 0.6 mm. in diam- 
eter. The luteal cells are filled with the red granules. There is a mass 
of blood in the center and practically no organization of connective 
tissue or blood-vessels. The left ovary contains six corpora lutea of 
the late red-granule stage. They have increased in size to 0.9 mm. x 
1mm. The normal development of the corpora lutea has apparently 
gone on in this ovary, as it compares very favorably with other ovaries 
of this date. There is no demonstrable pathology. 
