SUPRARENAL GLAND—EFFECTS OF INANITION Zal 
of the medulla parenchyma cells show a slight decrease in average 
diameter to 6.4 uw (normal 6.7 uw) and their relative volume de- 
creases to 17.2 per cent (normal 23.5 per cent). 
3. In young rats refed after stunting 
Table 4 shows the results in four individuals, two refed one 
week and two refed two weeks after being held at maintenance 
(nearly constant body weight). In general, the dimensions are 
slightly greater in those refed two weeks, but as the differences 
are usually slight, the average is given for the whole group. 
Comparison is made with the data for the maintenance group 
and for the normal. 
In cell diameter the cells of the outer cortical zone have in- 
creased to about normal size (from 8.1 » at maintenance to 8.7 y). 
The cells of the outer part of the middle zone have increased 
materially ( rom 11.1 » maintenance to 11.8 » after one week of 
refeeding and to 13.1 uw after two weeks), but are still below the 
normal. The inner-zone cells have increased to about normal 
size (9.2 u). The medulla cells have increased in diameter (from 
11.4 at maintenance to 12.2 uv), though still below normal 
average (13.2 yu). 
In nuclear size the outer-zone nuclei remain unchanged in di- 
ameter, though decreasing slightly in relative volume (percentage 
of cell volume). The middle-zone nuclei have not changed much 
in diameter, but on account of the increase in cell volume their 
relative volume has decreased to nearly normal ratio. The in- 
ner-zone nuclei have increased somewhat in diameter, so the 
nucleus-plasma ratio is now nearly normal. In the medulla the 
nuclei have apparently decreased in average diameter (to 6.1 u 
as compared with 6.4 uw at maintenance), and this reduces the 
nuclear percentage of the cell volume from 17.2 per cent to 12.9 
per cent, which is considerably below the normal (about 16 per 
cent). This nuclear change is difficult to understand. 
