a 
DEVELOPMENT OF UTERINE GLANDS 205 
toward the muscular coat. These folds are quite deep and are 
apparently constant, as they have been observed by other 
investigators and we have found them in older uteri. On the 
outer rim of these crescentic folds there are small outgrowths, 
which, we conclude from a study of later stages, are the rudiments 
of glands. The outgrowths have enlarged ends and _ short, 
constricted-necks. Occasionally these structures are found also 
at the edge of the uterine lumen, but are found nowhere except 
in these two places. 
In a one-day-old child, the glands, developing from the folds 
of the mucosa, sometimes form a row (fig. 2). The stalks of 
the glands are constricted with closely crowded, enlarged, 
flattened end pieces. 
There is only slight modification of this shape in a seven- 
month-old child uterus (fig. 3). The side of the uterine lumen 
was chosen for reconstruction. This specimen showed, as did 
several others, a lumen which in transverse section was boot- 
shaped. Glands grow from the ends of the heel and toe parts, 
as well as from lesser folds. Some of the glands have developed 
into a T-shape with the original short constricted neck, but 
with an enlarged tubular end extending at right angles to the 
stalk. In some only one arm has developed, forming an in- 
verted L-shape. In both the T and L glands, the end piece 
sometimes has longitudinal furrows, showing partial separation 
of the end piece into two parallel tubular branches. 
A model of a four-year-old specimen shows several of the 
features mentioned above. The crescentic folds of epithelium 
described in a six-month fetus are present here (fig. 4). At 
their outer rims are folds of well-developed glands. The T-shaped 
glands prevail and occasionally the tubular end pieces have 
divided, forming parallel tubular branches. Some glands, 
however, are very simple, being small evaginations with occa- 
sionally constricted necks. 
Several changes have taken place in the uterine glands of a 
fourteen-year-old child before puberty. These are evidenced 
by the further division of the T- and L-shaped glands. Some 
glands are still simple, showing short narrow stalks and two 
