THE LAC^HRYMAL GLAND 205 



More often, however, they are irregularly distributed through- 

 out the cell. In all the cells of the tubules the mitochondria 

 appear as ver}^ short irregular rods or as minute spheroids which 

 may be slightly irregular in outline. In no instance have I 

 seen long rods, threads, or loops as described especially for grow- 

 ing cells. Further, in the tubule the mitochondria do not form 

 rows in the base of the cell and perpendicular to its base (fila- 

 ments) such as found in the larger duct cells. Careful study 

 failed to reveal any general irregularity in the quantity of these 

 fuchsinophil granules. While some cells appear to possess more 

 than do others yet the light cells (type 1) which represent the 

 maximum of the granular stage apparently possess approxi- 

 mately the same number as do the dark cells (types 2 and 3) 

 which represent either earlier or later stages of secretion granule 

 formation. The mitochondria in these cells are not numerous 

 when contrasted with those seen in the cells of the intralobular 

 ducts (Cf. figs. 14 and 15). Consequently the granules do not 

 appear to be used up in the formation of secretion granules. 



Intercalary duct. The secretion granules in the intercalary 

 duct are well preserved in Bensley's acetic osmic bichromate 

 solution. In fact, so far as the preservation of secretion gran- 

 ules is concerned the effect of this solution is similar to Zenker's. 

 The granules here have a marked affinity for the methyl-green. 

 Between these green granules red stained mitochondria are 

 readily observed. They simulate those in tubules so far as 

 size, shape and distribution are concerned. 



Larger ducts. In the intralobular and interlobular ducts the 

 mitochondria are especially abundant. In the smaller intra- 

 lobular ducts they may be so numerous that the entire cell, with 

 the exception of the nucleus, appears to be composed entirely of 

 these fuchsinophil granules. In these cells there exist marked 

 irregularities so far as their distribution and arrangement are 

 concerned. Some cells may be full of these granules while 

 others again possess but relatively few. Generally the granules 

 are arranged in rows — these rows being parallel to each other, 

 perpendicular to the base of the cell, and extending through- 



