ACTHOR 8 ABSTRACT OF THIS PAPER IftSCED 

 BT THE BIBLIOGRAPHIC SERVICE, MAT 29 



NOR.MS FOR SO.ME STRUCTURAL CHANGES IX THE 

 HUMAN CEREBELLU.M FRO.M BIRTH TO OLD AGE 



ROBERT S. ELLIS 

 The Wistar Instilule of Anatomy and Biology 



EIGHT CHARTS 



111 a i)revious paper (Ellis. '19) I reported the results of a 

 quantitative study of the Purkinje cells in normal, subnormal, 

 and senescent human cerebella; the variations in the number of 

 these cells in different cerel)ella were correlated with differences 

 in muscular strength and in the develojiment of motor co()rdina- 

 tion. However, the results presente<l for the decrease in the 

 number of Purkinje cells with atlvancin^ age were based on such 

 a small number of cases that it seemed desirable to extend the 

 observations and to determine with more certainty the accuracy 

 of some of the conclusions reached. This has been done, and 

 the results of the further study are presented in this j)a]ier. In 

 addition, I have reviewi'd tlie literature on the growth of the 

 human cerebellum, have added some original t)bservations, and 

 have attempted to give a rcsumd of .some imi)ortant normal — 

 not pathological — structural changes in the cerebellum from 

 birth to death in old age. \'ariat ions from the norm have been 

 observed, and as far as possible these structural changes have 

 been correlated with changes in motor efhciency. 



For the increase in the weight of the cerebellum during growth 

 I have used the results of Boyd ('01), i)anielbe!vo; ('85), and 

 Pfister ('97-'03); on the significance of the relative weight of the 

 cerebellum I have reviewed the work of Gall (1807), Leuret ('39), 

 Hatai ('15), Marshall ('92), Bischoff ('80), :\Ieynert ('07), Weis- 

 bach ('00-'07), and Spitzka ('07), and I have calculated the rela- 

 tive weights of 152 cerebella from data given by ]\Iall ('09) and 

 by Bean ('06), and to this I have added the relative weights of 



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