CELLS OF THE NERVUS TERMINALIS OF THE RAT 101 



noch keine positiven Anhaltspunkte vorhanden. Allerdings ist 

 es moglich, dass solche in der Folge noch beigebracht werden." 



Apparently Disse should be added to the list of investigators 

 who have dealt with the origin of the ganglion cells of the nervus 

 terminalis, and v. Lenhossek to those inferring their existence. 

 Indeed, the work of Disse is so noted by Dollken ('09). His 

 ('89), too, perhaps should be added to the roll. In a human 

 embryo of four weeks His described cells resembling neuroblasts 

 in the olfactory epithelium. With the assumption of a bipolar 

 form these cells deserted the confines of the epithelium and in an 

 embryo one week older they were found connected with the 

 central nervous system on one hand and with the olfactory 

 epithelium on the other. 



From the general description given by Disse it would seem to 

 the writer that the ganglion cells of which he treats are those 

 which later investigators assign to the nervus terminalis, and a 

 similar interpretation is doubtless to be placed on those studied 

 by Pogojeff and His. A discussion of the papers of Locy, Johns- 

 ton, Belogolowy, and Brookover is unnecessary. Their papers 

 are too well known and besides have been considered but re- 

 cently by Larsell. In later investigations — those of McKibben 

 ('14), Huber and Guild ('13), and Larsell ('18, '19), it is quite 

 universally agreed that by far the majority of the ganglion cells 

 of the nervus terminalis are of the multipolar variety. Bipolar 

 cells are nevertheless encountered — by Larsell ('18) in consider- 

 able numbers. In view of the predominance of multipolar cells 

 in the ganglionic clusters of the nervus terminalis attempts have 

 been made to derive them from sources known or supposed to 

 furnish cell contributions to the sympathetic ganglionic masses 

 of the head. Such a tendency is to be noted in the interpreta- 

 tion suggested by Hardesty ('14) that the ganglion cells of the 

 nervus terminalis are to be thought of as belonging to the general 

 forward growth of the trunk sympathetic into the head region — 

 a supposition which the writer ('20) has considered scarcely 

 tenable. It again finds expression in the more recent suggestion 

 of Larsell ('19), that the ganglion cells of the nervus terminahs 

 originate from two sources — one of which consists in migratory 



