Table 5. Acute toxicities of selected PCDD isomers to 

 the guinea pig and the mouse (Kociba and Schwetz 1982b). 



PCDD isomer 



Oral LD-50, in ug/kg body weight 

 Guinea pig Mouse 



2,8-di COD 

 2,3,7-tri CDD 

 2,3,7,8-TCDD 

 1,2,3,7,8-penta CDD 

 1,2,4,7,8-penta CDD 

 1,2,3,4,7,8-hexa COD 

 1,2,3,6,7,8-hexa CDD 

 1,2,3,7,8,9- hexa CDD 

 1,2,3,4,6,7,8-hepta CDD 



>300,000 



29,444 



2 



3 



1,125 



73 



70-100 



60-100 



>600 



>3,000 

 284 

 338 



>5,000 



825 



1,250 



>1,440 



Table 6. Acute oral toxicities of 2,3,7,8-TCDD to mammals. 



Organism 



LD-50, in ug/kg 

 body weight (ppb) 



Reference 



1,2 

 3 



3 

 2 

 4 

 2 

 2 

 4 

 2 



^References: 1, Harless et al. 1982; 2, Kociba and Schwetz 1982a, b; 

 3, Silkworth et al . 1982; 4, Olson et al . 1980a, b. 



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