Literary Notices. cxvii 



elliptical shape, becoming more and more round as it becomes smaller, 

 until it disappears altogether. All stages of degeneration were observed 

 in the Purkinje cells of the ataxic specimen." 



"The Granular Layer. In the normal specimens the granules 

 in the region adjacent to the Purkinje cells are larger than the others, 

 but no structural differences are displayed. The layer of granules is al- 

 ways thickest at the summits of the folii, and thinnest at the bottom. 

 There is no regular arrangement in their distribution, save that where 

 thickest they are found in small groups. We were unable to detect any 

 difference in the appearance of the granular layer of the ataxic specimen 

 as compared with that of the normal, save that in the affected portions of 

 the ataxic, the line of demarcation between this layer and the Purkinje 

 cells is less clearly drawn, and that also in the ataxic, the granules near 

 the Purkinje cells are oftentimes more angular in shape and, on the 

 whole, less closely packed and less numerous in the ataxic than in the 

 normal. The medullary fibres from the central white portion form a net- 

 work throughout the whole of the granular layer." 



"The Condition of the Spinal Cord. A few scattered degen- 

 erated fibres were found in the column of Burdach, especially in the cer- 

 vical and lumbar regions, but these are restricted and apparently local, 

 since they could not be followed in the thoracic cord. 



There was no trace found of any inflammatory process, or any sort 

 of hemorrhage, and the symptoms manifested by the cat were such 

 that, when taken with the thinning and arrested development of the cor- 

 tex, we are led to describe the disease as a case of simple atrophy, which, 

 of course, is not an explanation. As already intimated, certain degener- 

 ations were found in the spinal cord, but in the main study these were 

 not followed out in detail." 



"(I). General Conclusions. The general fact, ;so well sustained by 

 measurements recorded in the table, that in the normal specimens the 

 molecular layer of the left hemisphere of the cerebellum is thicker than 

 that of the right hemisphere. In only five instances was there a prepon- 

 ating thickness of this layer on the right half, and since, in the character- 

 istic cat's cerebellum, the vermis is turned rather to the right of the mid- 

 dle line, these exceptions might readily be accounted for." 



"(2). A marked growth in the thickness of the molecular layer of the 

 six months' cat, as over against the one three months old, is also indicated 



