102 Journal of Comparative Neurology. 



ending seemed indicated, it was interpreted as showing imper- 

 fect staining. 



Berkley's (60) results on the innervation of the submaxil- 

 lary gland of the rat stained with his modified Golgi method, 

 confirm in the main results obtained by preceding investigators. 

 On the ultimate ending of the nerves he has this to say, — two 

 kinds of terminal endings exist : supracellular, here the ending 

 lies on the extreme outer edge of the cell, the fibril ending in 

 a small bulb, which rests in a pit-like depression of the surface 

 of the cell ; and inter-epithelial, pf less frequent occurrence, the 

 nerve fibril ending in the cement substance between the cells. 



I wish finally to refer to a communication from Arnstein 

 (61), "On the Morphology of the secretory nerve-appa- 

 ratus." In this article Arnstein gives a summary of results ob- 

 tained by himself and several of his pupils on the ultimate end- 

 ing of nerves in the following glands, — mammary gland by 

 Dmitrewsk ; skin glands by Ostrowmow ; prostate by Timo- 

 fiew, and the pancreas, salivary glands and Harder's gland by 

 Arnstein. Their results are summarized as follows, — the gland 

 nerves form around the secreting tubuli or alveoli, a plexus — 

 epilamellar plexus — which rests on the membrana propria ; from 

 this fine fibers are given off, which pierce the membrana, and 

 as peri-cellular fibers, without forming a network, and with or 

 without further branching, end on the gland cells in small 

 varicose endings, the configuration and complexity of which 

 varies for different cells, even in the same gland. These results 

 were obtained largely on macerated and teased preparations 

 made from glands stained in methylen-blue. In such prepara- 

 tions it was often possible to obtain isolated cells, showing the 

 terminal nerve apparatus in connection with short segments of 

 the pericellular nerves. And, if the account of Arnstein is to 

 be trusted at all, he has given us the most complete description 

 of the terminal ending of nerve fibers in glands. The nature 

 of these endings may be seen in Fig. 5, taken from Arnstein's 

 article. 



I have thus reviewed the literature touching on the subject 

 in question, partly on account of its importance, also to show 



