Huber-DeWitt, Nerve- Endings in Muscles. 193 



is, however, rarely seen. That the endings are on the cells, and 

 not in them or in the nucleus, may be ascertained in the occa- 

 sional cross sections through the muscle cells and nerve endings 

 which are here and there met, or perhaps more clearly 

 in the oblique sections now and then obtained. See Fig. 24 ; 

 also shown in Fig. 44 of Schultz's article. 



These results, as may be seen from the following quotation, 

 agree very closely with the results obtained by Mviller with the 

 Golgi method: " Die feinen Zweige endigen mit einer keulen 

 oder birnenformigen Anschwellung die sich auf eine Muskel- 

 zelle legt. Diese Anschwellungen sind sehr konstant und 

 regelmassig ihrem Aussehen nach, so dass ich keinen Anstand 

 nehme, sie als ein der Wirklichkeit entsprechendes Structur- 

 verhaltniss anzusehen. Es ist indessen nicht nur an den Enden 

 der Faden, wo sich solche befinden. Man findet namlich oft die 

 Faden ihrer ganzen Lange nach mit dergleichen kleinen Flatten 

 versehen, oft an kleinen kurzen Stielen sitzend und eine jede mit 

 ihrer besonderen Muskelzelle in Verbindung tretend. " 



Schultz, who has more recently worked on the ques- 

 tion, with both the Golgi and the methylene blue method, 

 reaches identical results as to the ending of the motor fibers in 

 involuntary, smooth muscle. He describes, however, another 

 system of nerve cells and nerve fibers, which may here be 

 briefly mentioned, although somewhat foreign to the subject in 

 hand. Schultz states that in methylene blue preparations, he 

 has observed a large number of nerve cells in the muscular tis- 

 sue of the intestinal wall. From these, longer or shorter pro- 

 cesses are given off, which pass out between the muscle cells. 

 These processes show varicosities and swellings toward the end 

 of the branches, to some extent also along the processes ; these 

 swellings and nodules are looked upon as an end-apparatus. In 

 the more fortunate preparations, he has recognized longer pro- 

 cesses, which are not varicose and do not branch, and which 

 could now and then be traced into a neighboring nerve bundle. 

 These cells, according to Schultz, form the sensory nerve sup- 

 ply of smooth muscle; and he states that we may find in them 

 an explanation of the severe pain which is now and then experi- 



