ox A LAW OF SPECIES IDENTITY OF THE NUCLEUS- 

 PLASMA NORM FOR NERVE CELL BODIES OF 

 CORRESPONDING TYPE 



THE NUMERICAL CONSTANCY OF THE NUCLEUS-PLASMA COEFFI- 

 CIENT OF THE FUNCTIONALLY RESTING PURKINJE CELL 

 OF THE DOG SPECIES 



DAVID H. DOLLEY 



From the Pathological Laboratory of the University of Missouri 



SIX FIGURES (one PLATe) 



CONTENTS 



Introduction 445 



Source of material 449 



Technical methods 453 



1. The calculation for aggregate cells from the average of measurements . . 453 



2. The calculation for the individual cell from serial sections 454 



a. By wax reconstruction 454 



b. By application of the prismoid formulas 455 



The numerical statement for the dog of the species constancy of the nucleus- 

 plasma coefficient of the functionally resting Purkinje cell 456 



The more exact definition of the resting cell resulting from the species 



identity 462 



The technical factors in their relation to the results 465 



1. In the method of average of measurements 465 



2. In the method of wax reconstruction 470 



3. In the application of the prismoid formulas 473 



4. In fixation and staining 474 



The biologic factors of deviation from a constant nucleus-plasma relation 475 



The significance of a constant nucleus-plasma relation for every cell of a type 



within a species 492 



Summary 495 



Conclusions 497 



INTRODUCTION 



In an earlier paper CIO), the writer called attention to the 

 fact that the nucleus-plasma coefficient of the resting Purkinje 

 cell was a close numerical constant m three dogs, one being an 

 undisturbed normal animal, the second having been exercised 



445 



