266 KIYOYASU MARUI 



stands out sharply, and the net beams are demonstrated in rigid 

 dark Unes. 



In many cases of fatigue this net configuration appears more or 

 less irregular and less sharply marked. The net beams present 

 themselves swollen and thick here and there; in other places they 

 are thinner than usual and in some places even broken up. The 

 substance of the net beams looks loose and less compact and in the 

 extreme state of decay the net beams are reduced to variably 

 large amorphous corpuscles and look not unlike silver precipitates 

 distributed irregularly in the synapse. 



Figure 7 was reproduced from, the Levaditi preparation of a 

 fatigue case; it shows the surface section of a slightly shrunken 

 Mauthner cell and the cell surface is covered partially with the 

 Golgi network. The reticular structure of the synapse stands in 

 this case in a more advanced state of alteration. The spheroidal 

 or star-shaped structures, which correspond to the nervous ter- 

 minal feet, are demonstrated very distinctly in the nodal points 

 of the Golgi network (especially clear in the lower part of the fig- 

 ure). Now, the net beams connecting these terminal feet with 

 each other are in part marked tolerably sharply, but most of them 

 are swollen and are not clean cut. Some others look, on the con- 

 trary, very thin and loose or even broken up. Here and there we 

 find the terminal feet, which lie isolated on the cell surface, as a 

 consequence of the breaking up of the radiating net beams. The 

 reticulum of the axone cap (upper part of the figure) is in a similar 

 state of alteration; the net beams are extremely swollen and 

 loosened and appear thick. The reticular figure is partly well 

 preserved, although we find here and there the decay of the net 

 beams. 



Figure 8 was produced from another case prepared by means 

 of Levaditi's method; the Golgi network in the axone cap as 

 well as on the cell surface shows essentially similar changes. 

 The net figure here and there is preserved tolerably well, but the 

 meshes are irregular as compared with those in the resting condi- 

 tion. In other parts of the synapse the net beams show a more or 

 less advanced state of alteration and some beams are really re- 

 duced to amorphous black fragments. 



