280 KIYOYASU MAEUI 



3. The nucleus was also either swollen or shrunken; in the 

 swollen nerve cell it was sometimes removed to one side of the 

 cell body. The nucleolus was also found swollen sometimes and 

 other times shrunken and it was of angular or otherwise irregular 

 shape. 



4. In the nervous structure of the synapse no definite altera- 

 tion could be brought out; but the synapse showed a number of 

 amoeboid glia cells with methyl-blue, fuchsinophil, and meta- 

 chromatic basophile granules. Also fat drops were demonstrated 

 in the glia cells and in the cells of the blood-vessels. 



5. The reticular glia structure of the synapse appeared in 

 many cases of fatigue in more or less advanced deviation from 

 its normal configuration and even broken up in somfe parts; 

 this was interpreted as the result of the detachment of the 

 amoeboid glia cells from the reticulum, as also the effect of the 

 loosening and dissolution of the net beams. 



6. The appearance of the amoeboid glia cells showed that some 

 catabolism process occurs in the synapse as the effect of patho- 

 logical nutrition conditions in fatigue. 



