Literary Notices. xv 



sions. A firm pedicle was found attached to the skull or falx at the 

 region of the longitudinal sinus. The tumor was shelled out and then 

 the capsule and pedicle were removed with the curette. A large rent 

 in the superior longit. sinus resulted, which caused profuse hemor- 

 rhage, which was controlled by gauze packing. Dressing was ap- 

 plied for three days, after which most of the gauze was removed — all 

 of it after four days more. After the operation complete motor par- 

 alysis of arm and leg for 24 hours, which continued to diminish until 

 nearly complete restoration. The tumor was diagnosed as endothe- 

 lial fibro-sarcoma. 



Microscopical Changes in Huntington's Chorea. 



Greppin reports a case, age 51, marked by dementia, refusal of 

 food, somnolence and general choreic movements. Autopsy revealed 

 pachymeningitis and leptomeningitis, also sclerosis of the septum 

 cranii. Convolutions were flattened and slight atheroma of vessels 

 of the base. Microscopic examination showed accumulations of nuclei 

 in both gray and white matter. Ganglion cells were sometimes oblit- 

 erated by them and the vessels whose walls were modified. In many 

 places these cells are agglomerated, losing their nuclei and making a 

 formless mass. The masses are distributed in the white matter of the 

 temporal, parietal, and frontal convolutions and in the cortex of the 

 insula and in the white matter of the cerebellum. They were less 

 numerous in the central ganglia, pons, and medulla. The medullated 

 nerves were reduced and the myelin sheaths swollen. The author 

 considers the cells modified connective tissue elements and considers 

 the case one of non-purulent encephalitis. 



The author differentiates the pathological state from that of gen- 

 eral paralysis by the statement that in the latter there are chiefly alter- 

 ations of the vessels and great modifications of Deiter's cells, while 

 in chorea there is a multiplication of cell elements. (Schmidt 's Jahrb. , 

 June 15, 1893.) 



Pathology of Hay Feyer. 1 



Dr. S. S. Bishop states that hay fever is due to an excess of uric 

 acid in the blood. Attacks may be prevented by reducing the amount 

 of uric acid to the normal or may be cured by precipitating the excess 

 of this substance. Leflaive found uric acid in great excess just prior 



! A New Pathology and Treatment of Nervous Catarrh. Jour. Am. Med. 

 Assoc, Nov. 25, 1893. 



