HYPOPHYSIS AFTER CASTRATION 



447 



TABLE 1 



Average diameters of cells in ventral glandular portion of hypophyses of normal 

 male albino rats at various ages; average of 10 in each case 



The size of the two distinct glandular cell types is shown in 

 table 1 and also the size of the reserve cell nuclei. According 

 to the measurements there is continued, though slight, growth of 

 the basophiles throughout the period measured, but there is 

 little change in the acidophiles. In one normal specimen, 136 

 days old, were found basophiles containing large vacuoles, and 

 consequently of a ring shape. This has also been reported re- 

 cently by Jackson ('17). 



In the glandular cells is seen a cytoplasmic structure, the 

 nature of which is at present under discussion. After the methods 

 of fixation of Bensley and of Cowdry mentioned above in "Ma- 

 terial and Methods," it is more evident than after fixing fluids 

 containing acetic acid. I have referred to it in the description 

 of the figures as the macula. It appears in these preparations 



TABLE 2 



Average diameters of normal and experimented acidophiles at varying periods 



after operation. Normal and experimented animals from same litter at 



each age. Average of ten measuretnents in each case 



