STUDIES ON THE OLFACTORY BULBS OF THE ALBINO 
RAT—IN TWO PARTS 
I. EFFECT OF A DEFECTIVE DIET AND OF EXERCISE 
II. NUMBER OF CELLS IN BULB 
CAROLINE M. HOLT 
From The Wistar Institute of Anatomy and Biology! 
FOUR PLATES 
PARTI. EXPERIMENTS TO DETERMINE THE EFFECT 
OF A DEFECTIVE DIET AND OF EXERCISE UPON 
THE WEIGHT OF THE OLFACTORY BULBS 
CONTENTS 
Pp nO GUC lO Mess cet ae Clk alee Aussi S's 2, ws GROMER AM GAIA eg oc dolteh rene ees 202 
PE Wetectuve diet experimenter ti. 4.2.2... eames sae ee AO. os 204 
1. Previous experiments on the effect of starvation upon the central 
NELV OUR SV Scena OF “Ghe Tats es. cen. Ae oe tate eee 204 
2. Series A: Aj, rats on defective diet from time of weaning at eighteen 
to twenty days, and Az, at thirty to thirty-two days........ 205 
Bite WECTHOGNG sien Sood tte ehh: CS TRG ERS See SRR AEE A tM te, 205 
Dae sUled sate ays the Ai eeace ee. cts sk dt ee ee eee ean en ee 207 
General morphological, and physiological modifications. ... . 207 
Effect on brain and olfactory bulbs......................-. 209 
3. Series B. Rats on defective diet from birth...................... 210 
ce UC t NO Gieie cnn RO Say dh pe eo An, Rebel wera eave Mn hers 210 
peeve Slts  Oitn GF teesd | aan Wiese See emert tsb. se beksenmen. ay t,t edie: 214 
ih PSETRISS ( CISUIS TIC. Uh 7: SR ae eR de me eR ge, E(t ae 215 
SUMINE SUGGES Sere ei gaw a cae AL ae ne ee occ er ey cate ereiels eee. t, 215 
5. Summary and conclusions: Defective diet experiments........... 217 
Ty xe reise ex peninentses td smi ee BoM ON eae Ly 219 
1. Previous experiments on the effect of exercise upon the albino rat.. 219 
2. Description of experiments: Series D and E...................... 220 
3. Series D: Rats in revolving cages for thirty days................ 221 
Be RESIS PINS soo, 2 ine sch Awe ARM Se Ln SO SS 221 
‘Thesis presented to the Faculty of the Graduate School of University of 
Pennsylvania in partial fulfillment of the requirements for the degree of Doctor 
of Philosophy. 
201 
THE JOURNAL OF COMPARATIVE NEUROLOGY, VOL. 27, NO. 2 
