PRIMARY AND SECONDARY FINDINGS IN A SERIES 
OF ATTEMPTS TO TRANSPLANT CEREBRAL 
CORTEX IN THE ALBINO RAT 
ELIZABETH HOPKINS DUNN 
From the Marine Biological Laboratory, Woods Hole, Mass., and the Anatomical 
Laboratory of the University of Chicago 
EIGHT FIGURES 
INTRODUCTION 
This paper is to report the findings of a somewhat extended 
attempt to transplant cerebral cortex. In two instances, at 
least, the attempt to keep alive the neurons within the tissue 
seemed to meet with success, although not in the manner de- 
sired, since the tissue transferred from one animal to a second 
animal became adherent in a position such that the extending 
axons could not grow into adjacent nervous tissue. 
The secondary findings have some interest also, and the en- 
tire problem has a value because of its bearing on the question 
of the vitality of nervous tissues. Continuation of the life and 
growth of nervous tissue in vitro has been accomplished suc- 
cessfully, Harrison, ’07, Burrows, 711, Lewis, ’12, but the per- 
petuation of the vitality of nervous tissue transferred from one 
region of the nervous system to another region has met with 
greater difficulties. 
In the earlier attempts at transplantation it was found that 
the transplanted mass did not disintegrate entirely and disap- 
pear, but that the neurons died, leaving the supporting struc- 
tures to represent the original transplanted portion. Of the earlier 
attempts at transplantation those of W. Gilman Thompson, 
90, of Saltykow, ’05, and of Del Conte, ’07, may be cited. In 
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