A CASE OF CYCLOPIA 195 



The specimen was preserved immediately after death, under 

 Dr. Le Count's direction, by an injection through the carotid 

 artery of 10 per cent formalin (4 per cent formaldehyde) after 

 which the whole body was immersed in a solution of the same. 

 On account of this careful fixation, the histological preservation 

 was excellent. 



A research had been begun upon this specimen before it came 

 into my possession, and on this account I have been unable to 

 determine the exact attachments of the cerebral roof over the 

 tha'amic mass. I am indebted to Miss Katherine Hill, medical 

 artist at the Hull Laboratory of Anatomy, for the four drawings 

 of the entire brain made shortly after its removal from the skull 

 cavity and before the relations referred to above had been 

 disturbed. 



GENERAL DESCRIPTION OF THE CASE 

 External features 



The body is that of a well developed male infant weighing 

 se\'en and one-half pounds. The head is enlarged and shows a 

 condition of moderate hydrocephalus so that the cranium cere- 

 brale is considerably more developed than the cranium viscerale. 

 The skull is dolichocephalic, though not markedly so, as is usu- 

 ally the case in hydrocephalus (18) It measures 95 mm. in 

 greatest transverse diameter, and 130 mm. in greatest longitudinal 

 diameter, the cephalic index being 73. The sagittal suture is 

 widely open, the parietal bones being separated from one another 

 by a considerable space (2 to 3 cm.) throughout. The metopic 

 suture is also widely open, its lateral margins being separated 

 in the upper part by a distance of 10 mm. 



At the base of the regio frontalis, which is high and prominent, 

 in the mid-line is a finger-like process of about 2 cm. in length. 

 The walls are firm and it presents at its distal extremity a single 

 orifice which leads into a blind passage extending inward as far 

 as the attached end of the organ. This appendage, which proba- 

 bly represents an abortive naso-frontal process, overhangs the 

 single median eye (fig. 1). 



