TRANSPLANTATION OF LIMBS IN AMBLYSTOMA 147 
limbs still farther removed from the normal region should exhibit 
little if any movements. Such was found to be true, since in 
twelve experiments so performed there occurred only one (case 
AS7;) in which any motion was observed and this consisted of 
a slight flexion of the carpus. This individual was sectioned and 
studied. The limb was found to be innervated from the tenth 
and eleventh segments of the cord (table 2). The shoulder- 
muscle innervation was quite defective. ‘The number of cases 
of this series being small, they have not been included in the 
table. 
Résumé of autoplastic experiments. Viewing the autoplastic 
experiments as a whole, we find that as the limbs become trans- 
planted more and more remote from the normal situation there 
occurs a corresponding decrease in their ability to function until 
a position is reached (series AS6) in which all limb movements 
are very imperfect, there being no cases with perfect adaptive 
function. This gradual decrease, in so far as movements of the 
shoulder are concerned, is unquestionably determined by a 
gradual decrease in the peripheral innervation; yet, the decrease 
in the function of the forearm, wrist, and hand is not based 
upon defective limb innervation. Further, the gradual loss of 
coérdination as the limbs are farther and farther removed from 
the normal site must be conditioned by factors other than its 
peripheral innervation. These factors, which are thought to 
be most important in conditioning the function of the limbs in 
the various positions, will be more fully discussed later on. 
B. Homoplastic transplantations with normal limb intact 
The homoplastic experiments consisted in transplanting an 
additional anterior limb rudiment a given number of segments 
posterior to the normal intact limb, the respective series being 
designated as HS3, HS4, and HS5. 
The results of these experiments when compared with those 
of the autoplastic experiments furnish additional evidence which 
explains more fully the factors underlying the function of trans- 
planted limbs. 
As has already been pointed out, the normal anterior limb 
rudiment occupies a region extending from the anterior border 
