178 M. F. GUYER AND E. A. SMITH 
was practiced. It seems worth while to call attention to this 
intravenous method, inasmuch as some of the most pronounced 
effects produced in the uterine young were secured with serum 
from fowls which had been thus intravenously treated and had 
- later been further sensitized or resensitized by the intraperitoneal 
method. 
The rabbits were generally so mated as to have the young in 
utero somewhere near the ten-day stage of development at the 
time of the first injection of fowl serum. Only albino rabbits 
were used, as it was thought that the unpigmented iris would be 
of advantage in examining the lens and the interior of the eye. 
In the following detailed account of our later series of experi- 
ments, the first experiment of the new series is recorded as ‘Ex- 
periment 10’ in order to keep the designations the same as in our 
office records, and also to avoid confusion with the experiments 
discussed in our former paper (718). All injections into the rab- 
bits were intravenous unless. otherwise specified. Unless the 
eyes were visibly defective, they were recorded as normal. 
Experiment 10 
In this experiment five fowls and three rabbits were used as 
specified in table 1. The chief purpose of the experiment was 
to find if lens-defects could be induced in the young of rabbits 
far advanced in pregnancy. Only two injections were given. 
It will be observed that the fetuses of two of the rabbits, numbers 
13 and B, were within about nine days of birth when the first 
serum was introduced. Apparently: the dose, 8 cc., was too 
large. 
The evidence indicates that the young were killed in utero in 
all three of the mothers. Each doe became very ill, and B died 
two days after the second treatment. Dissection showed that 
she was carrying five young. Judging from their somewhat 
macerated condition, they had been dead some days. The other 
two does acted as if crippled. They did not recover from their 
stiffness and lethargy for several weeks. Our inference was that 
the young were gradually resorbed, or perhaps in the case of the 
one with young far advanced, aborted. The latter idea is based 
