AUTHOR’S ABSTRACT OF THIS PAPER ISSUED 
BY THE BIBLIOGRAPHIC SERVICE, JULY 12 
FACTORS INFLUENCING THE GROWTH OF A TRANS- 
PLANTABLE TUMOR IN MICE 
CyCe LITTLE 
Carnegie Institution of Washington, Cold Spring Harbor, New York 
TWO DIAGRAMS AND ONE FIGURE 
This paper has for its object the analysis of certain of the 
factors underlying susceptibility and non-susceptibility of mice 
to implants of a sarcoma (J. W. B.) of the Japanese waltzing 
mouse. 
An effort has already been made and is still being continued 
to determine the number and nature of the genetic factors under- 
lying the successful growth of the tumor. Such experiments will 
' be reported on in a future paper. In the meanwhile, however, 
the effects of age and sex upon the growth of the tumor have been 
studied in certain races of mice and form the subject-matter of 
this communication. 
MATERIALS 
a. Tumor. ‘The tumor used is a sarcoma (J. W. B.) described 
by Tyzzer (15), which originated in a closely inbred strain of 
Japanese waltzing mice. When a bit of the tumor is implanted 
subcutaneously in mice of this race, growth of the implant is 
continuous, resulting eventually in a large subcutaneous tumor 
and death of the animal. By means of such implants, this tumor 
has been propagated within this race for seven years, or for over 
forty implant generations. 
b. Mice. The 675 mice used were of two races: 1) Common 
non-waltzing animals of (a) albino and dilute brown (dbr) 
stocks, and, 2) hybrids produced by crossing these common 
races with Japanese waltzing mice and then back-crossing the 
first generation hybrids with the common non-waltzing parent 
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