354 



E. I. WERBER 



(fig. 1) it is seen that the eyes are greatly deformed, only their 

 pigmented parts being discernible. The right eye appears to be 

 rather small, while the left eye is large and protruding and ex- 

 hibits striking evidence of dissociation. Transverse sections 

 {QfjL in thickness) show the following conditions : 



Already in the second section there can be seen at the base of 

 the forebrain on both sides a number of small lentoid bodies. 



I 2 



Fig. 1 Teratophthalmic embryo, twenty-nine days old, from acetone solu- 

 tion (20 cc. gram molecular in 50 cc. sea water). Exposure one hundred and 

 forty-four hours, solution renewed every day. 



Fig. 2. Teratophthalmic embryo, twenty-three days old, from the same ex- 

 periment as the embryo in figure 1. 



which if followed in succeeding sections are found to form an 

 almost continuous mass. In the same section one still smaller 

 lentoid is seen on the periphery of the integument, while in 

 further sections nearly all of the strata of some parts of the epi- 

 dermis seem to be transformed into such lentoids. At this level 

 (48^1 from the tip of the head, figure 3)'' there is seen at the base 

 of the brain a fairly large lentoid with a number of smaller ones 

 near by. All lentoids so far recorded in this description are in a 

 stage of differentiation transitional between the epithelium of 

 the lens-bud and the fibrillae of the fully developed lens. FoUow- 



^ It is a pleasure to acknowledge my indebtedness to Professor Petrunkevitch 

 for his kind assistance in making the photomicrographs. 



