618 Sergius Morgulis 
VI STIMULATION AND DEPRESSION OF PROTOPLASMIC ACTIVITY 
AS DYNAMIC FACTORS IN REGENERATION 
The present chapter is based upon experiments which were 
performed in 1907, and then repeated in 1908. It will be con- 
venient to give first the results of each experiment of 1907 and 
then the results of the corresponding experiment performed the 
following year. 
If regeneration is a function of the entire organism, it must be 
' dependent upon the physiological condition of the organism, 
and should, therefore, be subject to acceleration and retardation 
on altering the physiological condition. This hypothesis was 
put to the test of experimentation, of which the following chapter 
is the outcome. 
First Series of Experiments 
In this set of experiments was tested the effect of alcohol and 
chloretone. 
Experiments with Alcohol 
-A large number of worms cut anteriorly to the middle of the 
body were subjected to the action of a solution of alcohol and 
sea-water, in the concentration of 1:25,000. The treatment 
extended over one-third of the time of the experiment only and, 
although none of the worms regenerated more segments than the 
worms with the largest number of new segments of the corre- 
sponding control, the effect of the alcohol was very definite. As 
compared with the control, there was a great preponderance of 
worms with large numbers of regenerated segments in the alcohol 
solution. A similar experiment was done in 1908, but this time 
the worms were kept in the alcohol solution during the entire 
period of their regeneration. ‘The results were more positive 
as will be seen from the data given in Table XI. 
The middle column contains the data for the control, the right 
and left columns contain those of experiments with alcoholic 
solutions of I : 10,000 and I : 20,000 concentration respectively. 
The number of regenerated segments in the control varies from 
