Physiology of Regeneration 631 
In Table XXIII are recorded the results of the experiment 
with the I : 1,000,000 solution of strychnine. The number of 
new segments varies from 2 to 6, and the average number of 
regenerated segments as well as the numerical relation of those 
segments to the old segments are lower than the corresponding 
numbers in the control. 
Table XXIV, which refers to worms treated with 1 : 10,000,000 
solution shows very much the same thing, although the effect is 
not quite as distinct as in the previous case. 
Thus strychnine produced a depressing effect upon the regen- 
erating worms, which resulted in a lowering of the index of regen- 
eration by about 5 to 7 per cent as compared with that of the 
control. 
Experiments with Pilocarpine Hydrochloride 
Solutions of pilocarpine hydrochloride in sea-water were pre- 
pared of three different strengths—1 : 100,000, I : 1,000,000 and 
I : 10,000,000. ‘The first of these solutions was too poisonous 
in its action, and as already stated, caused death to all of the 
worms. 
In Table XXV are given the data of an experiment with the 
0.0001 per cent solution of pilocarpine (1: 1,000,000) upon the 
regenerating worms. 
TABLE XXV 
AUGUST 3I-SEPTEMBER 14 (1907) NUMBER OF SEGMENTS AVERAGE 
| 
: ; Old | 17 | 18 | 18 | 18 | 19 | 18 | 18 18 
Pilocarpinie st) 251,000,000 aissle\=-1-/e's\¢.5,s1/«/0le)¢/ <1 Newhal ay Allad ateete 4-3 
The average number of segments here is 4.3 and comparing 
these data with those of the control (Table XXII) it will be found 
that the regenerative power of the worms suffered a reduction. 
In Table XXVI are presented the data with regard to the action 
of the 0.00001 per cent solution of pilocarpine (1: 10,000,000) 
upon the regenerating worms. 
