692 A. Ff. Goldfarb 
interesting experiments along the lines laid down by Morgan, and 
came to a similar conclusion. He used Nereis diversicolor and 
instead of operating in the head region, he cut a strip, including 
nerve cord and muscles, near the posterior end of the animal. In 
others he destroyed the cord and surrounding tissues with a hot 
needle. Autotomy of some or all of the injured segments took 
place so that the new tail grew from a more anterior level. Care- 
ful examination was made of those animals wherein at least 1 to 3 
cordless segments were left at the posterior end of the animal. 
He found that some time after the closing of the wound, fibers 
grew from the old cord toward the amputated end, and that the 
new tail did not regenerate until these fibers had reached the end 
avid supplied it with the proper nerve stimulus. Then a rapid pro- 
liferation of ectoderm cells took place anteriorly, which, with the 
probable addition of cells from the old cord, provided the material 
for making of the new nerve cord. In the author’s own words: 
“Die mikroskopische Untersuchung zeigt uns, dass auch hier der 
Einfluss des Centralnervensystems keineswegs als ausgeschlossen 
betrachtet werden kann, da bald nach dem Wundverschlusse, 
welchen ich noch nicht fiir einen eigentlichen Regenerationsvor- 
gang halte, die Neubildung des Bauchmarkes in denjenigen Seg- 
menten, in welchen dasselbe fehlte, und zwar unter gewisser 
Mitwirkung des alten Bauchmarkes, stattfindet, und dass erst, 
nachdem diese Neubildung stattgefunden hat, die E:gentliche 
Regeneration, d. h. die Bildung einer Proliferationszone, vor dem 
Analsegment erscheint und die Entwickelung eines Regenerations- 
kegels zustande kommt,” and more poignantly “Dass Die Anwesen- 
heit des Centralnervensytems die eigentliche - Regeneration der 
feh'enden Kopersegmente gewissermassen bedingt, oder mit and- 
ern Worten, dass die eigentlichen Regenerationsprozesse vom Cen- 
tralnervensystem auf irgendwelche Weise beeinflisst werden.” 
Retzius ( 92) showed quite clearly that—in the earthworm—each 
segment is innervated by motor nerves that take their origin in its 
own segment or in the next adjoining and possibly in the next two 
segments.® On the <upposition that the distribution of nerves in 
®Havet, J., also showed this for lumbricus and other worms in his “Structure du Systéme ner- 
veaux des Annélides,” La Cellule, vol. 17, 1900. 
