EFFECTS OF DRUGS ON WHITE MICE 129 



At eight weeks the control mice averaged 19.5 grams in weight, 

 the alcohol mice 18 grams, the nicotine mice 18.5 grams and the 

 caffeine mice 16 grams. At twenty-four weeks the control mice 

 averaged 24 grams, the alcohol mice 24 grams, the nicotine mice 

 22 grams and the caffeine mice 23 grams. At thirty-six weeks 

 the control mice averaged 27.3 grams, the alcohol mice 19.5 

 grams, the nicotine mice 22 grams and the caffeine mice 27.6 

 grams. 



The control mice gained 4.5 grams each in the first sixteen 

 weeks of the experiment and 3.3 grams in the last twelve weeks. 

 The alcohol mice had gained 6 grams each when twenty-four 

 weeks old, but had lost 4;5 grams on an average at the end of 

 the experiment. The nicotine mice gained 3.5 grams each by the 

 twenty-fourth week, and had gained no more at the end of the 

 experiment. The caffeine mice gained the most of all, 7 grams in 

 the first sixteen weeks and 4.6 grams in the last twelve weeks. 



The average gain for the alcohol mice was 1.5 grams, for the 

 nicotine mice 3.5 grams, for the control mice 7.8 grams and for 

 the caffeine mice 11.6 grams. 



WEEKLY ACTIVITY OF THE MICE 



The number of revolutions registered by each clock was recorded 

 at 12.30 P.M. every day. In the following tables the number of 

 revolutions that each mouse ran are recorded by weeks. 



Mouse No. 1 exhibited its greatest activity from the tenth to 

 the eighteenth week, then became somewhat less active, increased 

 again at the twenty-fifth week and then decreased rather gradually 

 till the end of the experiment. Its maximum run was 139 078 

 revolutions at the thirteenth week and its minimum run was 

 48 380 revolutions at the thirty-fourth week. Its average run 

 per week was 92 004 revolutions. 



No. 2 exhibited its greatest activity from the eleventh to the 

 seventeenth week and then had a second period of high activity 

 from the twenty-fifth to the twenty-ninth week. Its maximum 

 run was 147 576 revolutions at the fourteenth week and its mini- 

 mum run was 59 320 revolutions at the thirty-fifth week. Its 

 average run per week was 95 622 revolutions. 



