338 



C. M. JACKSON 



parison of tables 3 and 4. The direct nuclear measurements 

 were made in a larger number of cases (12) and therefore give 

 a somewhat better idea of the amount of individual variation. 



The dh'ect measurements of nuclei, as shown in table 4, were 

 made for the pars intermedia as well as the pars anterior. Con- 

 sidering the latter first, measurements were in most cases made 

 separately for the eosinophile and non-eosinophile (including 





Fig. 5 From a photograph showing a small part of the anterior lobe of the 

 hypophysis in an adult rat (M 12) subjected to chronic inanition. Marked 

 effects of inanition: hyperemia; atrophy and loss of specific staining reactions 

 in cytoplasm; hyperchromatism and pycnosis of nuclei. Zenker fixation; haema- 

 toxylin-eosin stain. X 440. 



basophile and chromophobe) cells. In the earlier normal stages 

 there does not appear to be any constant difference in nuclear 

 size between the two classes of cells. But later, and especially 

 in the rats subjected to inanition, the average is less for the 

 nuclei of eosinophiles. This is probably because the eosinophiles 

 appear more prone to karyopycnosis. 



The nuclei of the pars intermedia cells do not differ much in 

 size from those of the pars anterior, especially of the non-eosino- 



