:^7() ARTJIIH WILLIAM MEYER 



In the ^oal the location and a|)i)eMraiice of lieiiial nodes were 

 entirely comparable to tiiosc in the sheep as Warthin, '02b then 

 stated, except that from the six carcasses and two adult animals 

 examined 1 am compelled to conclude that they are far less 

 numerous. Subcutaneous hemal nodes were not found. In 

 one goat, a healthy and well-fed animal, for example, which was 

 examined several houis after accidental death, only two flat- 

 tened henuil nodes approximately 3.5 mm., in size were found 

 directly beneath the peritoneum near the aorta in the left 

 supra-renal region. These specimens were proven to be hemal 

 nodes by injections and although the rest of the carcass was 

 examined carefully, no other nodes were found. 



In a second animal, which I owe to the courtesy of my for- 

 mer colleague. Professor Zinsser, no larger number of hemal 

 nodes was found, although this animal had received repeated 

 injections of living typhoid bacilli for a period of nine months. 

 With the exceptions of a few intermissions, this animal had been 

 given intravenous injections of one-third to seven slants of ty- 

 phoid cultures in increasing doses, every five days at first, and 

 later every ten days. The total number of doses given was 

 twenty-six and Professor Zinsser stated that precipitin against 

 typhoid was present, that the blood showed a very high agglu- 

 tinating power (1-2000), gave a bacteriolytic titre of 1-4000 in 

 vitro test, and also showed a slight inhibition (1-10,000). Yet 

 only a few hemal nodes were present in this animal. In fact, 

 they were fewer in both these goats than in the six carcasses 

 of adult animals examined in abattoirs. Nor did the lymph 

 nodes of this goat show any change whatever as judged by 

 naked eye appearances. These facts are particularly signifi- 

 cant in view of the opinion of Meek, '10 regarding the 

 effect of toxins in the production of hemal nodes which was dis- 

 cussed elsewhere (Meyer, '14) in connection with the results of 

 experiments on guinea pigs. 



In the carcasses of the six other goats, a total of only about 

 six to twelve nodes was present in the abdominal and thoracic 

 cavities. Subcutaneous hemal nodes were never seen. All 

 nodes were verv small — 1 to 3 mm. — and no so-called mixed 



