DEVELOPMENT AND FITNCTION OF HEMAL NODES 



393 



lines can be seen but the appearance of the specmien is more 

 uniform, the nuclei are considerably smaller and the beginning 

 of reticulum formation is suggested by the appearance of some 

 of the mesenchyme cells. In some small portions of the periph- 

 ery the formation of spaces is also indicated. 

 • Although it is difficult to determine the exact relation of the 

 capillaries ^ present in the surrounding mesenchyme to these 









Fig. 10 Somewhat older aulagc of a similar node. Foetus 32 cm. X 720. 



small nodules neither of them was formed in or near a plexus 

 of any kind. Hence if as I have good reason to believe, these 

 nodules represent very early stages in the development of hemal 

 nodes there can no longer be any doubt as to their formation 

 as inde]3endent differentiations in the subcutaneous mesenchyme. 

 \Xi^ In the next earliest stage which I happened upon the dif- 

 ferentiation of the node has progressed a good deal as shown 

 in figure 11. In this specimen which measures one third milli- 

 meter, the syncytium is gone and the cells are quite distinct. 



