398 



ARTHUU WILLIAM MEYER 



the inislciicliii^" apix^tirancos recorded above, the foriiiation of 

 the fat lobule follows a quite different course than that followed 

 by the hemal node. Hence confusion is impossible except per- 

 haps in its very early forms when the fat lobule too is repre- 

 sented merety by a slight condensation in the mesenchyme as 

 represented in figure 3. 



Fig. 14 Peripheral vessel coininunicating with the siil)c:ipsular blood space. 

 Foetus 30 cm. X 1050. 



From the evidence obtained so far I feel justified in conclud- 

 ing that the development of subcutaneous hema! nodes in bo- 

 vines begins as differentiations in the mesenchyme. The earliest 

 anlage is syncytial and the first cells which are circular or poly- 

 gonal in outline are rather large but are not abundantly provided 

 with protoplasm. The nuclei are large and vesicular the whole 

 cells recalling the large leucocytes of mature lymph nodes. The 

 so-called peripheral sinus seems to form in loco wholly inde- 



