REACTION OF LYMPHATIC ENDOTHELIUM 



425 



most cases, however, the globule retained approximately the 

 same position throughout the period of observation. 



Soon after the injection of olive oil, leucocytes were observed 

 to pass through the walls of nearby blood-vessels and to wan- 

 der toward the oil. Upon reaching it, they flattened out and 

 formed a ring of cells around the periphery of the globule. A 

 few minutes after coming in contact with the oil, the leucocytes 



11:40 A.M. 



12:00 Noon 



12:10 P.M. Q 



-'c? V 



12:20 PM.CX O 



Fig. 1 Series of records illustrating the first reaction of leucocytes toward 

 the various substances injected. In this case a globule of oleic acid was in- 

 jected eighteen hours before this series of sketches was drawn. Immediately 

 after injection it changed to a brown opaque mass. At the time of making these 

 records it consisted of a dense brown central portion and an outer portion, con- 

 taining small refractile oil globules and surrounded by a ring of leucocytes. 

 During the observations, leucocytes were seen to pass out of neighboring blood 

 vessels and to approach the injected mass, where they were seen to take up the 

 brown pigment and small oil globules. Some of the leucocytes containing pig- 

 ment were seen to wander away. These records show clear leucocytes A B D G H 

 and F approaching the injection mass and becoming pigmented. W, Y and Z, 

 leucocytes which came out of the blood vessels and moved toward the injected 

 mass. C D and V, pigmented leucocytes which wandered away from the in- 

 jected mass. B.V., blood vessels; lym., lymphatic. Enlargement = 168x. 

 Drawn with camera lucida. 



