REACTION OF LYMPHATIC ENDOTHELIUM 447 



b. Leucocytes respond quickly to the injected substances, 

 migrate toward them in large numbers and actively engulf the 

 fat. 



c. The fat is absorbed, apparently, through the combined 

 efforts of leucocytes and lymphatics'. 



d. Mesenchyme cells and blood-vessel endothelium are un- 

 affected in any observable way by the presence of the injected 

 fat. 



e. The rapidity of absorption depends upon the size of' the 

 fat droplets : the fine emulsions of cream and yolk of egg are taken 

 up very much more quickly than the single relatively large 

 globules of olive oil and oleic acid. 



f. The fat appears to be changed within the leucocytes and 

 to be absorbed in a soluble form by the lymphatics. 



BIBLIOGRAPHY 



(1) Bloor, W. R. 1915 Studies on blood fat: fat absorption and the blood 



lipoids. Jour. Biol. Chem., vol. 23, p. 317. 



(2) Bloor, W. R. 1916 Fat assimilation. Jour. Biol. Chem., vol. 24, p. 447. 



(3) Clark, E. R. 1909 Observations on living growing lymphatics in the 



tail of the frog larva. Anat. Rec, vol. 3, no. 4, p. 183. 



(4) Clark, E. R. 1912 Further observations on living growing lymphatics: 



their relation to the mesenchyme cells. Am. Jour. Anat., vol. 13, 

 p. 351. 



(5) Clark, E. R. 1916 A study of the reaction of mesenchyme cells in the 



tad-pole's tail toward injected oil globules. Proc. Amer. Assoc, of 

 Anat., Anat. Rec, vol. 10, no. 3, p. 191. Also, Anat. Rec, vol. 11, 

 no. 1, p. 1. 



(6) Clark, E. R. and E. L. 1917 A study of the reaction of lymphatic endo- 



thelium and of leucocytes, in the tad-pole's tail, toward injected fat. 

 Proc. Amer. Assoc, of Anat., Anat. Rec, vol. 11, no. 6, p. 342. 



(7) D'Errico, G. 1907 Contributo alio studio delle Vie di Assorbimento del 



Grasso Alimentare. Arch, di Fis., vol. 4, Fasc. 6, p. 513. 



(8) Evans, H. M. 1908 On the occurrence of newly-formed lymphatic ves- 



sels in malignant growths. Johns Hop. Hosp. Bull., vol. 19, no. 209, 



(9) Evans, H. M. 1912 tiber das Verhalten der Lymphgefasse bei experi- 



mentell erzeugter Peritonealcarcinose der Maus. Beitr. z. Klin. 

 Chir., vol. 78, p. 109. 

 (10) Fiessinger and Marie 1909 Les Ferments dcs Leucocytes dans les 

 Exsudats des Sereuses. C. r. de 1. Soc de Biol., 1909, p. 1062. Also, 

 Jour, de Physiol., vol. 11. p. 746. 



