author's abstract of this paper issued 

 bt the bibliogkaphic service, april 11 



MITOCHONDRIA AND GOLGI APPARATUS OF THE 

 GIANT-CELLS OF RED BONE-MARROW 



H. E. JORDAN 



Department of Histology and Embryology, University of Virginia Medical School 



TWO PLATES (fourteen FIGURES) 



INTRODUCTION 



This investigation was undertaken with the view mainly of 

 adding to our knowledge of the giant-cells of red bone-marrow. 

 Whatever information might accrue with respect to the signi- 

 ficance of mitochondria and the Golgi apparatus was a secondary 

 and incidental consideration. Only giant-cells of the hemogenic 

 series come within the scope of this investigation. This work 

 has no reference to the osteoclasts. 



In connection with previous studies of the medullary giant- 

 cells, numerous unsuccessful efforts were made, extending over 

 several years, to demonstrate in the extensive cytoplasm of these 

 giant-cells, by various standard technics, mitochondria, an 

 internal reticular apparatus of Golgi, and the trophospongium 

 of Holmgren. A recent more intensive application to this 

 specific aspect of the general problem of the structure and 

 significance of the hemogenic giant-cells, consisting mainly of 

 experiments with modifications of the several fixing fluids in 

 more general use for the demonstration of these structures, has 

 yielded positive results with respect to both mitochondria and 

 the Golgi apparatus, and more or less provisional results regard- 

 ing the so-called trophospongium. 



MATERIAL AND METHODS 



The material employed was the femoral marrow of the rabbit 

 and guinea-pig, both infantile and adult. The method that 



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