author's abstract of this paper issued 

 by the bibliographic service, june 27 



STUDIES ON THE STRUCTURE AND MULTIPLICATION 

 OF BONE CELLS FACILITATED BY A NEW 



TECHNIQUE 



T. H. BAST 

 Department of Anatomy, University of Wisconsin 



ONE PLATE (six FIGURES) 



CONTEXTS 



Introduction 139 



Technique 140 



Observations on cell structure 142 



a. Shape and size of bone cells 143 



b. Relation of cells to lacunae 144 



c Protoplasmic processes of bone cells 144 



d. The cytoplasm 145 



e. The nucleus 145 



/. The centrosomes 145 



g. Multiplication of bone cells 146 



Literature and discussion of bone cell 147 



a. Relation of cells to lacunae and canaliculi 148 



b. Multiplication of bone cells 149 



c. Discussion 150 



Functional consideration 151 



Summary 153 



Bibliography 154 



INTRODUCTION 



According to the generally accepted view, a bone cell may 

 be defined as a modified, functionless or senile osteoblast. The 

 osteoblast or bone-former is a characteristicly changed fibroblast. 

 Certain fibroblasts become rounded and are transformed into 

 osteoblasts which arrange themselves on the surface of the bone 

 spicules where they deposit osseous substances. The origin of 

 the fibroblast is somewhat different in the two types of bone. 

 In membranous bone the fibroblasts arise in situ from the mesen- 

 chyme while in cartilaginous bone they are carried by the osteo- 



139 



