author's abstract op this paper issued 

 by the bibliographic service, august 5 



ABSORPTION FROM THE VENTRICLES IN EXPERI- 

 MENTALLY PRODUCED INTERNAL 

 HYDROCEPHALUS 



G. B. WISLOCKI AND T. J. PUTNAM 

 Laboratory of Surgical Research, Harvard Medical School 



FOUR FIGURES 



Internal hydrocephalus has been produced experimentally in 

 several ways. Dandy and Blackfan ('13, '14) reported the suc- 

 cessful production of an obstructive hydrocephalus in dogs 

 following the introduction of pledgets of cotton into the aqueduct 

 of Sylvius. Thomas ('14) described an internal hydrocephalus 

 produced in dogs by the intraventricular injection of aleuronate. 

 The aleuronate caused a sterile inflammatory reaction which 

 occluded the ventricular cavities at one or more points and 

 prevented the escape of the cerebrospinal fluid into the subarach- 

 noid space. Subsequently, Dandy ('19) produced a communica- 

 ting type of hydrocephalus by placing strips of gauze, saturated 

 with iodine, about the mesencephalon. 



Recently, Weed ('20) described the results of his experiments 

 on a series of young and adult cats. He was able to produce 

 an internal hydrocephalus with great facility by injecting a 

 suspension of lampblack into the cisterna cerebellomedullaris 

 through a puncture in the occipito-atlantoid ligament. It was 

 found that the lampblack caused a sterile meningitis about the 

 rhombencephalon, thereby gradually occluding the foramina in the 

 roof of the fourth ventricle and preventing the escape of cerebro- 

 spinal fluid into the subarachnoid space. Hydrocephalus was 

 also produced by intraventricular injections of the lamp black. 



Weed's experiments on kittens in which the fontanelles had not 

 united are mainly of interest. In these animals hydrocephalus 

 developed extremely rapidly and the dilatation of the ventricles 



313 



