TEMPERATURE SENSES IN FROG S SKIN 



101 



side of the toe was pricked, the normal foot never failed to react, 

 though care was taken that the needle did not pass through 

 underlying tissue. 



TABLE 10 

 Responses in seconds to pain and heat. Pain stimulations hy pricking the side 

 of the fifth toe. Right foot cocained 50 minutes. Left foot normal. Reaction 

 allowance, 30 seconds. Stimulation time, 2 minutes, co = no response 



This comparison of pain and heat was first tried upon the 

 normal feet with a regular, sudden, and vigorous response to the 

 pricking and the characteristic jerk and extended reaction time 

 after heat stimulation. The response to heat was ehminated or 

 greatly retarded by the fifty minutes' treatment with cocaine 



