author's abstract of this paper issued 



BT the bibliographic SERVICE, MARCH 27 



THE TRANSPLANTATION OF SKIN IN FROG TADPOLES, 

 WITH SPECIAL REFERENCE TO THE ADJUSTMENT 

 OF GRAFTS OVER EYES, AND TO THE LOCAL SPECI- 

 FICITY OF INTEGUMENT 



WILLIAM H. COLE 



Zoological Laboratory, Harvard University 



TWO TEXT FIGURES AXD FOUR PLATES (tWENTY-TWO FIGURES) 



CONTENTS 



Introduction 354 



Material and methods 357 



General observations 360 



1 . Pigmentation 360 



2. Description of the healing process 363 



3. Proliferation of the transplants 365 



Mechanical adjustment of grafts 367 



1. Grafts over eyes kept in the light (series LN) or in darkness (series 



DN) 367 



a. Tail skin 367 



b. Back skin 377 



2. Grafts not over eyes (series LB) or over operated eyes (series LO). . . . 378 



3. Grafts over artificial eyes, series LBE and DBE 383 



Local specificity of integument 386 



1 . Normal integument 386 



2. Autotransplants 387 



3. Homoiotransplants 390 



Acquisition of melanophores by white grafts on a black region 395 



1. Autotransplants 395 



2 . Homoiotransplants 396 



Pigmentation of the conjunctiva caused by injury 401 



General summary and conclusions 405 



A. Mechanical adjustment of grafts over eyes 405 



B. Local specificity of integument 406 



C. Acquisition of melanophores by white grafts on a black region 406 



D. Pigmentation of the conjunctiva caused by injury 407 



E. Reactions of the melanophores 407 



Literature cited 408 



353 



