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old, menstruates regularly every four weeks the periods lasting from 
four to five days. She gave birth to a child September 19, 1892 and 
had the first recurrance of menstruation December 19. The second 
period followed on January 25 and was very profuse; it lasted until 
February 1. The next period should have begun about February 22, but 
on account of its lapsing the patient concluded that she was pregnant 
and called at my office a few days later. I did not examine her, but 
asked her to remain quiet and await developments, as I thought possible 
that she might be pregnant. On the evening of March 1 she fell and 
sprained herself and during the same night had a scanty flow. The flow 
recurred each day and on the seventh of March she passed the ovum. 
It was kept in a cool moist cloth for twenty hours, and when it came into 
my hands was at once placed in a large quanty of 60 °/, alcohol“ !). 
The ovum is quite large for its age having a long diameter of 
10 mm and a short diameter of 7 mm. It is covered with villi only 
around its greatest circumference having two spots without villi, as was 
the case with Ricuert’s ovum. The villi of the chorion are from 0,5 
to 0,7 mm long and are branched. 
Upon opening the chorion it was found that the germinal le 
was situated just opposite the border of the zone of villi. About it was 
much coagulated albumen which I did not remove and therefore could 
not obtain good camera drawings. The portion of the chorion to which 
the vesicle was attached was cut out and stained with alum cachineal 
and cleared in oil, but even after this treatement it was impossible to 
obtain any clear picture. The specimen was next imbedded in paraffin 
and cut into sections 10 w thick. The series proved to be perfect. 
From the sections a reconstruction was made in wax and the accom- 
panying figure is a sagittal section of it. 
The sections and reconstruction show that the embryonic vesicle 
is attached to the chorion by means of a stem (Bauchstiel). The 
vesicle itself is composed of two layers between which, at a distance 
from the stem, there are indications of blood-vessels or a middle em- 
bryonic layer. Just beside the attachment of the vesicle to its stem 
there is a deep and short invagination of both layers of the vesicle. 
The walls of the invagination are somewhat thicker than those of the 
surrounding vesicle. The dimensions of the different portions of the 
vesicle are as follows: 
1) Letter from Dr. Kırırever, April 27, 1893. 
