774 
yellowish hue than its surroundings. Around this comes a series of 
fine fibrillae with extensions into the lighter-colored inner zone, which 
is partly surrounded by dense aggregations of very fine and coarse 
interlacing fibrillae, so stained as to appear dark colored masses with 
low powers, and from this central mass come off extremely fine and 
medium sized wavy fibrillae, that in the best specimens obtainable, 
are seen entering between the liver cells and permeating all the ad- 
jacent tissues; the appearance being very similar to that described by 
Mau (7) in his treatise on reticulated tissue (in the liver), and is pro- 
bably identical with it. The fibrillated tissue immediately surrounding 
medium sized arteries is occasionally stained in the same manner as 
that around the portal veins, but coarser fibres come closer to the 
vessel’s lumen, and extensions into the surrounding spaces are not so 
extensive, but few of the fibrillae being tinged within the intra-lobular 
regions. The best specimens are always to be had where the central 
vein is stained, and from such a specimen fig. 1 is drawn. 
With a few exceptions, all the fibres composing the peri-arterial 
networks are exceedingly fine, and though they interlace in every di- 
rection, definite branchings do not occur, or if present, are not suf- 
ficiently distinct to be determined, therefore it cannot be said that a 
distinct fibrillary plexus exists. 
Nerves have not been found very frequently intermingled with 
these reticulated fibres, occasionally a single filament may be seen as 
in the figure, running with or crossing the fibrillae; more often small 
nerve bundles may be seen in the same field, but where over they 
are present, they are easily distinguished from the reticulated fibres 
by the difference in contour, their definite branchings, to some extent 
by their calibre, and the entire difference in color. 
The intrinsic nerves. 
The intrinsic nerves of* the liver separate themselves naturally 
into four divisions, all connected together and morphologically alike. 
So far as our researches have advanced, we have found no medullated 
nerve fibrillae, nor can precise reasons for their presence in a purely 
glandular body be advanced, though according to the anatomical text 
books, the organ receives filaments from both the pneumogastric and 
phrenic nerves. 
The first and most important division is that to the portal vein, 
with its manifold ramifications, inter- and intra-lobular; the second is 
to the branches of the hepatic artery; and the third is the distribution 
to the biliary ducts; while the fourth and last is the terminal plexus 
and proper endings between the hepatic cells themselves, which are 
