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@,@,a,a nerve fibrillae and bundles. 2, 5 intercellular branches are seen, with a 
<c, an arborization. d the biliary canal in outline. e outline of a portion of a portal 
vein. /f inter-lobular connective tissue. Picrie acid. 
Fig. 3. Outline drawing of the central vein of a lobule with surrounding nerve 
fibres. a sheath of vein, 5, 5 nerve fibres around the vein, e globular endings close to 
the sheath of the vessel. d,d short inter-cellular branches with end-knobs. e longer 
ramus ending upon a liver cell. GoLGI preparation. 
Fig. 4. Nerves and their branches surrounding a portion of a hepatic artery, the 
artery in outline a 6 margin of the lobule, c, e branching and anastomosing fibres. 
d ganglionic thickening of a fibre, e intercellular branch, with f,f rami from it, and 
at g, a forked ending with knobs. Acid picric. 
Fig. 5. Portion of a biliary canal. a connective tissue along the outer sheath, 5 
columnar epithelium, ce nerve fibre, with at d, a forked termination, the lower branch 
having a knob ending, the upper apparently penetrating the cement substance. GoLGI 
preparation. 
Fig. 6. Sectional drawing of a biliary duct with nerve fibres and inter-cellular 
branchings. Along the margin of the duct may be seen several endings in knob-form 
lose to the epithelial lining. a duct, 5 nerve fibres, c inter-cellular branch, with at 
d, a termination between the cells. Acid picric. 
glandular bodies, the peri-arterial networks are very poorly developed, 
which may be a defect of the stain; and usually all that is seen are 
a few twigs, or small bundles following the course of the artery, with 
a comparatively small number of branchlets and knob terminations 
the latter often closely approximated to the outer lamina of the vas- 
cular sheath, doubtless in relation to the smooth muscular bundles. 
Figures 4 and 10 are examples of the nerves grouped around arterioles. 
In the first example, besides a number of filaments grouped on either 
side of the vessel, a nerve fibre is seen to the left, which shortly 
anastomoses within the margin of the lobule with a branch coming 
from above, and, the united fibre continuing onward, has quite a wide 
distribution, giving off here and there inter-cellular branches, finally 
it ends with a forked termination at the margin of, and between two 
liver cells. Arteries having many more terminations than that pictur- 
ed in fig. 4 are everywhere to be met with, the usual form being 
numbers of scattered fibres, though often a distinct nerve bundle ac- 
companies the vessel, as the portal vein is followed in fig. 2. This 
is mainly with the larger stems, the smaller showing the scattered 
filaments. 
Contrary to expectation, we found the biliary ducts accompanied 
by nerve fibres — even when lying quite apart and separate from the 
main vessels.. The arrangement of these nerve fibres is very similar 
to that of the hepatic arteries, branches; but entirely distinct nerve 
bundles are found following them. The single nerve twigs running 
with the biliary canals course in the connective tissue between the 
