26 ROSS G. HARRISON 
as dorsoanterior ; one of these died early and the other two gave 
rise to imperfect Hmbs with indeterminate asjinmetry.^o 
The individual cases in which limbs of opposite asymmetry 
developed were rather more irregular than in the preceding 
groups, though the best cases gave perfect reversed appendages. 
In addition to the ones included in the tabulation, there is one 
other case that probably belongs in this category. It is one in 
which the orientation of the bud at the time of transplantation is 
recorded as uncertain. -^ The limb that developed is a perfect 
one of reversed asymmetry in nearly the same posture as the nor- 
mal limb of the side to which it was transplanted. It showed an 
unusual amount of motility. In one case, included in the records 
of this group,-- the transplanted bud developed into a normal 
Imib of the side from which it was taken. It is believed, however, 
that a mistake was made in recording the operation in this case, 
and that probably in reality the orientation of the limb was not 
inverted. The direction of pointing, as observed on the third 
and fifth days after the operation when the limb bud is recorded 
as pointing anteriorly, is evidence, though not absolutely conclu- 
sive, that an error has been made. If this interpretation is cor- 
rect, the case would not be exceptional, but would accord with 
the eight cases described in the previous section. 
In the eight cases in which reduplications occurrred, the early 
stages of development were like the normal (figs. 28 and 29), 
the reduplicating buds not being noted until at least twelve 
days after the operation. Three individuals showed distinctly 
that the primary limb was of reversed asymmetry. In one case 
it was so imperfect that it could not be determined to which side 
it belonged, but the reduplicating limb was sufficiently devel- 
oped to show that it was of the same side as the bud was origin- 
ally, indicating that the original member was in all probability 
reversed. Another case-^ gave a limb with nearly sj^nmetrical 
reduplication in the hand without anything to indicate which 
member was primary (figs. 31 and 32). Two long radial digits 
are present in the middle and two short ulnar digits on each side. 
Still another case^* gave a very peculiar result. The primarj^ 
20 Tr. E. 108 and 203. " Tr. E. 109. 22 Xr. E. 113. " Tr. E. 217. 
" Tr. E. 163. 
