SYMMETRY IN TRANSPLANTED LIMBS 33 
is quite separate from the rudimentary girdle developed from the 
tissues of the host (p. 59). 
The ten cases in which normal non-reversed limbs developed 
are clearly contrary to the rule (p. 4). The records of these 
casfes show that the end result is reached by a process of rotation 
at the shoulder-joint during development (figs. 56 to 58). They 
will be considered below (p. 40). The reduplicated limbs, of 
which there were twenty-seven, fall, like the single, into two 
groups. In the first the original bud developed into a limb of 
reversed asymmetry, while in the second it is not reversed. 
Observations upon the earlier stages of the operated limbs show 
that in those cases which give reduplications, as well as in the 
case of the simple limb with reversed asymmetry (figs. 35, 42, 
43, 49, 51, and 52), the original direction of pointing is either 
dorsal, anterior, or dorsoanterior, and more sharply lateral than 
normal. Likewise in the case of those that develop into single 
non-reversed limbs, the first pointing is more sharply lateral than 
normal, and also more dorsal, though only two^^ are recorded as 
pointing slightly anteriorly from the dorsal direction. This 
shows that the original tendencies of growth, immanent in the 
bud at the time of transplantation, are by no means inactive 
when it is in its new position. One or the other of two conse- 
quences of this growth tendency now ensues, indicating a sort of 
antagonistic reaction between the organization of the transplanted 
rudiment and that of the surrounding parts. The limb either 
continues to grow in an anterior or anterodorsal direction, in 
Figs. 35 to 41 Orthotopic transplantation; left limb to left side inverted 
(hom.dv.), resulting in a normal right limb on the operated side. E.xp. I. E. 64. 
TR, transplanted limb. X 10. 
Fig. 35 Lateral view, five days after operation. 
Fig. .36 Ventral view, ten days after operation. 
Fig. 37 Dorsal view, sixteen days after operation; transphinted limb covered 
by gills. 
Fig. 38 Lateral view of limb, sixteen days after operation. 
Fig. 39 Dorsal view, twenty-three days after operation. 
Fig. 40 Ventral view, twenty-three days after operation. 
Fig. 41 Lateral view, twenty-three days after operation. 
35 L E. 49 and 94. 
