108 ROSS G. HARRISON 
ever, there are four normal limbs and three redupUcations. If 
combined with the present results, this would reduce the dispro- 
portion somewhat, though it would still leave it very large. 
There are no cases of complete regulation over to the harmonic 
position either by rotation or reduplication. Moreover, redu- 
plication in over half the harmonic grafts disturbs the possible 
harmonic end result. 
As pointed out above, the case is very different in the orthotopic 
operations. Here the harmonic group produced twenty-four 
out of twenty-five (96 per cent) single limbs, while the dishar- 
monic group produced but twelve single limbs (17.4 per cent), 
ten of which became harmonic by rotation and are therefore 
omitted from the tabulation, and fifty-seven reduplications (82.6 
per cent), in three of which, however, the primary bud became 
harmonic by rotation and a possible adaptive result was pre- 
vented by the process of reduplication. Leaving out of consid- 
eration the cases in which single normal luiibs were produced by 
rotation, there are but two cases left (3.4 per cent) in which the 
disharmonic relation failed to be followed by reduplication. 
In a word, with orthotopic grafts the almost completely 
dominant factor in producing single limbs or reduplications is 
the harmony or disharmony of the combination, whereas the 
case is quite different in the heterotopic grafts, where the har- 
monic group produced a slight preponderance of reduplications 
and the disharmonic group a great preponderance of single limbs. 
At first sight the above figures might be advanced in support 
of some hypothesis of an end purpose in development, inasmuch 
as reduplications are produced in overwhelmingly great number 
only where ihey may be taken advantage of to produce an adap- 
tive end result. This, however, would be a hasty conclusion to 
draw. The orthotopic experiments may be explained as above 
(p. 106). There the tendency to reduplicate is due first to the 
disturbance of operation, which, being very slight, is almost al- 
ways suppressed in the harmonic combinations by the advantage 
the primary bud has in connecting normally with the surround- 
ings; while in the disharmonic combinations the tendency to re- 
duplicate is not only greatly increased by the reversal of the axis 
