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for the network or patches of basophilic material which are always 

 present. The same variations are found in the larger lymphocytes 

 with round nucleus which are not quite large enough to be classed as 

 large mononuclears, and also in the medium-sized cells. As already 

 stated, the polymorphonuclears differ from the larger lymphocytes 

 and large mononuclears merely in the general shape of the nucleus. 

 The cytoplasm remain unchanged, but, of course, may show the same 

 variations in the degree of basophilia, being strongly basophilic in 

 some of them. 



The character, number and distribution of the azurophil granules 

 is the same in the polymorphonuclear cells as in the larger lymphocytes. 

 Figures 1 to 4 give a good idea of their relative size, distribution and 

 number. Some of the granules are very fine dust-like particles, while 

 others are quite large; they are always distinct and sharply outlined, 

 and are stained a reddish-violet color with the Wright's stain. 

 When they are very numerous, as in figures 1 to 3, they give the 

 cytoplasm a diffuse reddish color which might easily be taken for a 

 general oxyphilic reaction of the cyptoplasm when the cells are viewed 

 with a low power. This mistake could easily be made when the baso- 

 philic spongioplasm is reduced to a minimum, leaving the inter- 

 granular protoplasm almost colorless. However, a good lens shows 

 that this apparent acidophilic reaction is due to the color of the vary 

 numerous granules. A considerable amount of basophilic material 

 is always present in the cells, and frequently it is so abundant that 

 the cytoplasm appears strongly basophilic. In cells of the latter type 

 the granules are, of course, not as distinct as they are in the cells which 

 are only slightly basophilic. Occasionally a cell, like the one shown 

 in figure 5, was found in which the intergranular cytoplasm appeared 

 to be slightly oxyphilic, and in which the granules were not numerous. 

 The character of the nucleus indicates that this is a very old cell. 

 About three of them were found in a dozen preparations, which shows 

 that they are very rare. They all contained granules, but they seemed 

 to be reduced in number. A small amount of basophilic spongioplasm 

 was also present in these cells. Frequently the granules show a radial 

 arrangement about the centrosphere, especially in the younger cells. 

 Figure 1 gives an idea of this arrangement, the centrosome being in the 

 concavity of the nucleus. 



The distribution of the granules is quite variable in the different 

 cells, as is seen from a study of the figures. They may be very nu- 



